Pain Management in Elizabethtown, PA

Expert care that helps you live better every day.

How Does Ketamine Work?

Ketamine works in the body by targeting key receptor sites in the brain to protect against excitotoxicity and restore balance in how information is processed. Research has revealed how ketamine's effects go beyond acting on glutamate receptors; it also influences areas tied to motivation, emotion, and behavior, including monoamine transporters and opioid receptors, allowing it to target a wider array of symptoms quickly. Those seeking help managing their mental health condition can rest assured that ketamine is a safe and effective option to explore.

Find Lasting Relief Close to Home

Chronic pain holds you back from the life you deserve.


On some days, you might skip morning walks with your furry friend or find simple tasks like shopping, cooking, or driving too challenging.


At Lisa Makrides, MD, PC, we listen closely and don’t just treat pain symptoms — we treat you. At our pain management clinic near Elizabethtown, PA, we take the time to understand how pain affects your daily life. Then, we design treatments that fit your unique needs, goals, and lifestyle—because no two pain stories are the same.


You don’t have to let pain control your day.



Schedule an appointment and take the first step toward lasting relief and getting back to doing what you love.

Get Ketamine Relief Today

When Pain Gets in the Way of Living

Living with chronic pain makes everything harder—working, sleeping, connecting with people you love. Even small joys like playing with the kids or enjoying the outdoors can feel out of reach.


You’ve probably searched for pain management centers near me or wondered if pain clinics in your area can actually help.


Maybe you’ve already seen specialists who rushed you through appointments, offered the same solutions you’ve already tried, or told you the pain was something you’d “just have to live with.”

It’s frustrating. It’s exhausting. And it’s not something you should settle for. 



Pain shouldn’t define your days. You deserve to be heard and treated as a whole person.

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Chronic Pain Affects More Than Just Your Body

Pain doesn’t just wear on your joints or nerves—it wears on your mental and emotional well-being too. 


According to research published in the Journal of Pain Research, individuals with chronic pain are significantly more likely to struggle with their mental and emotional well-being.


In fact, nearly 60% report symptoms of depression, and more than 50% show signs of anxiety — a clear sign that pain affects far more than your body.

You Deserve Relief That Lasts

Chronic pain doesn’t have to control your life. Taking action now can set you on the path to lasting relief.


At Lisa Makrides, MD, PC, we use proven, advanced treatments— including integrative approaches—to target the root causes of your pain. Our team works closely with you to create a customized plan that fits your goals, addressing both physical discomfort and emotional well-being.


Start taking control today with expert care right here in Elizabethtown, PA.

Advanced Treatments in Elizabethtown, PA

Finding the right treatment is key. That’s why we offer a variety of advanced, personalized therapies designed to meet your unique needs and goals.


Here are some of the advanced options we offer to target your pain from multiple angles:

Ketamine Therapy

Ketamine therapy is a carefully guided treatment led by board-certified medical professionals. It’s proven to help with mental health issues ranging from PTSD, addiction, to depression and anxiety.


The therapy works by balancing and resetting key receptors in your brain—glutamate receptors, plus monoamine transporters and opioid receptors—to help your brain process emotions differently.


It’s a safe and effective option to consider if you’re looking for a new approach to mental health care.

Prolotherapy

Prolotherapy supports your body’s natural healing to repair injured ligaments and connective tissue. Small injections of natural substances like dextrose trigger your body’s healing response to reduce joint and back pain.


It’s often used for arthritis, tendon injuries, and conditions like degenerative disc disease or fibromyalgia.


This safe, minimally invasive option may help improve your mobility and ease discomfort.

Medication Management

Medication management helps control pain from nerve damage, arthritis, fibromyalgia, and injuries. We carefully tailor your medications to provide relief while minimizing side effects and dependency risks. This approach prioritizes your safety and comfort, particularly for long-term pain management.

Integrative & Functional Approaches

These treatments combine medicine with holistic therapies like nutrition, physical therapy, and mindfulness. It addresses chronic pain, inflammation, migraines, and stress-related symptoms—plus the anxiety and depression that often come with ongoing pain. It’s about healing your whole self, not just the pain.

Rheumatoid Arthritis Treatment & Chronic Conditions

Specialized care focuses on reducing inflammation, managing joint pain, and preserving mobility for autoimmune and chronic inflammatory conditions, helping you maintain your quality of life.



Regardless of your pain, these treatments can help you regain control and return to the things that matter most. Let Lisa Makrides, MD, PC, guide you toward greater comfort and the freedom to enjoy your daily life again.

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Why Choose Dr. Lisa Makrides for Pain Management in Elizabethtown?

You’ve seen the treatment options—now here’s why so many patients in Elizabethtown trust Dr. Lisa Makrides with their care:



  • 20+ years of clinical experience treating complex pain and mental health conditions in Elizabethtown and the surrounding areas

  • Double board-certified in Physical Medicine & Rehabilitation and Pain Medicine

  • Whole-person approach that supports your physical, emotional, and mental well-being

  • Evidence-based therapies, including ketamine therapy, prolotherapy, and functional medicine

  • Convenient Elizabethtown location with flexible scheduling and easy access

  • Trusted affiliations with the American Board of Pain Medicine, ASIPP, and the Pennsylvania Medical Society

You’re not just getting a provider—you’re gaining a partner who truly listens, digs deeper, and helps you take back control.

Get Ketamine Therapy Near Elizabethtown, PA

What Elizabethtown Patients Are Saying

See what Elizabethtown patients say about our pain management clinic and the care that’s helping them feel like themselves again.

“She is a gem! She shows so much empathy.”

“Dr. Makrides has been my pain management doctor for about 4 years. She is a gem! She shows so much empathy and will keep trying strategies until she finds one that will make your pain more manageable. She is extremely knowledgeable and up to date on all new alternatives. I highly recommend her!” —Linda T.

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Frequently Asked Questions About Pain Management

Still wondering if this kind of care is right for you? Here are answers to the most common questions we hear from your neighbors across Elizabethtown and Lancaster County.

  • Is ketamine therapy legal in Pennsylvania?

    Yes. Ketamine therapy is legal in Pennsylvania when administered by licensed medical professionals. Our Elizabethtown clinic offers ketamine therapy under strict medical supervision for approved conditions like depression, anxiety, PTSD, and more.

  • Are there pain clinics near me that offer ketamine therapy?

    Yes. If you’re in Elizabethtown or the surrounding area, our clinic provides ketamine therapy as part of a personalized pain and mental health care plan.


  • What conditions are treated at a pain management clinic?

    We treat a wide range of chronic and complex pain conditions, including:

    • Fibromyalgia
    • Migraines and chronic headaches
    • Joint pain and arthritis
    • Nerve pain
    • Rheumatoid arthritis
    • Degenerative disc disease
    • Stress-related pain conditions

  • Do pain management clinics take insurance?

    Yes. We accept most major insurance plans and can assist you in confirming your coverage prior to your visit. Just give us a call.


  • What is functional pain management?

    Functional pain management combines traditional medicine with holistic care—like nutrition, movement therapy, and mental health support—to treat the root causes of pain, not just the symptoms.

Still Have Questions? Contact Our Elizabethtown Office

Start Healing Today

You deserve pain management in Elizabethtown, PA, that sees you as a whole person and supports your journey to lasting relief. At Lisa Makrides, MD, PC, we’re here to support you as you regain control and return to the life you want to live.

Begin Your Road to Recovery Today!