Ketamine Therapy in Lancaster, PA
When Traditional Treatments Haven't Been Enough
Looking for treatment near NYC?
We’ve opened a second office in Midtown Manhattan!
We’re excited to announce our new Midtown Manhattan location, providing physician-led ketamine therapy, personalized treatment plans, and compassionate care for NYC patients.
What To Expect During Ketamine Therapy
Before Treatment
Patients undergo a comprehensive medical and psychiatric screening, which may include:
• Review of medical history and prior treatments
• Medication reconciliation
• Assessment of treatment goals and appropriateness
Ketamine therapy is provided only when clinically indicated and medically appropriate.
During Treatment
Sessions take place in a private, calming treatment suite, where patients remain under direct medical supervision and have their vital signs monitored. Sessions typically last 40–90 minutes, depending on formulation and protocol. Many patients describe a temporary sense of relaxation or altered perception during treatment. These effects are expected, transient, and medically monitored.
After Treatment
Patients are observed until clinically stable, and same-day driving isn’t permitted. We discuss follow-up planning as part of an ongoing care strategy—ketamine therapy is often delivered as a series of treatments, with response evaluated over time rather than after a single session.
Available Ketamine Formulations
Treatment route and dosing are determined by the treating physician based on clinical indication, medical history, and patient-specific factors.
Intravenous (IV) Ketamine
Administered via controlled infusion in a monitored medical setting. Allows precise titration and predictable onset. Commonly used for both chronic pain and mood-disorder protocols.
Intramuscular (IM) Ketamine
Delivered by injection into a large muscle under medical supervision. Predictable absorption without the need for IV access. May be appropriate for selected patients based on clinical judgment.
Intranasal Ketamine
Administered as a nasal spray under medical guidance. Non-invasive option used in select mental-health protocols.
Oral / Sublingual Ketamine
Taken by mouth or absorbed under the tongue. Lower bioavailability and slower onset. Typically reserved for maintenance or carefully selected cases.
Safety is Our #1 Priority
At our Lancaster, PA, clinic, ketamine therapy is physician-directed with individualized treatment, conservative dosing, informed consent, and careful monitoring. Ketamine is not a cure; results vary, and every treatment decision prioritizes safety, appropriateness, and collaborative patient care.
How Much Does Ketamine Therapy Cost?
The cost of ketamine therapy in Lancaster, PA, varies based on your personalized treatment plan and the type of therapy recommended. During your consultation, Dr. Lisa Makrides will explain your options, discuss expected costs, and answer your questions so you can make an informed decision about whether ketamine therapy is the right choice for your needs.
What Our Patients Are Saying
"Dr. Lisa is the ONLY doctor who has taken the time to really help us. Before her, all the other pain management doctors did little to help us."
Sean O.
“Dr. Makrides has been helpful, professional, and the backbone of my care. She takes her time with me, very accessible if needed, and will go out of her way to make sure that I get any referrals done at the time of service. I highly recommend seeking her care. She’s the easiest to communicate with, in any case.”
Terra R.
Every patient's journey is different. See how personalized care, careful physician oversight, and ketamine therapy have made a difference in the lives of others.
Frequently Asked Questions
Here are some common questions about ketamine therapy and what you can expect during your treatment journey with Dr. Makrides.
Who is a good candidate for ketamine therapy?
A good candidate for ketamine therapy is someone living with treatment-resistant depression, anxiety, PTSD, certain chronic pain conditions, or other qualifying diagnoses that haven't responded well to conventional treatments. Every patient undergoes a comprehensive evaluation with Dr. Makrides to determine whether ketamine therapy is a safe and appropriate option based on their medical history, symptoms, and treatment goals.
How many ketamine treatments will I need?
The number of ketamine treatments varies depending on your diagnosis, symptoms, and response to therapy. Some patients begin with an initial series of treatments followed by maintenance sessions as needed, while others require a different schedule. Dr. Makrides will develop a personalized treatment plan and adjust it based on your progress and goals.
Will I need someone to drive me home?
Yes. Because ketamine can temporarily affect your alertness, coordination, and perception, you should arrange for a responsible adult to drive you home after your treatment. Dr. Makrides will provide detailed pre- and post-treatment instructions so you know what to expect and when it's safe to resume your normal activities.
Is ketamine therapy covered by insurance?
Insurance coverage for ketamine therapy varies depending on your insurance provider, diagnosis, and the type of ketamine treatment being recommended. Some treatments may be covered, while others are considered self-pay. Our team can discuss your options, explain potential costs, and help you understand what to expect before beginning treatment.
How long does each appointment take?
The length of each ketamine therapy appointment depends on the type of treatment you're receiving, but most visits last between 40 and 90 minutes. During your consultation, Dr. Makrides will explain what your treatment schedule will look like and answer any questions you may have.
How do I schedule an appointment?
Scheduling a consultation is easy. Simply call our office or complete the contact form on our website to request an appointment. During your consultation, Dr. Makrides will review your medical history, discuss your symptoms and treatment goals, and determine whether ketamine therapy is an appropriate option for your needs.
Safe & Successful Ketamine Treatment in Lancaster, PA
If you've spent years trying medications, therapies, or other treatments without the relief you hoped for, it may be time to explore a different path. Ketamine therapy in Lancaster, PA, with Dr. Lisa Makrides combines innovative treatment with thoughtful medical oversight, helping you make informed decisions based on your symptoms, history, and long-term goals, not a one-size-fits-all approach.