Pain Management in Lancaster, PA

Find Relief. Restore Your Life.

No one should have to live in pain—especially when proven, non-surgical treatments are available right here in Lancaster County.

NO ONE SHOULD BE LIVING IN PAIN

Every task takes longer. Every movement drains more energy than it should.


Pain changes the way you work, connect, and enjoy the people and activities you love. Even the simplest moments can feel like a challenge.


At Dr. Lisa Makrides, MD, PC, we provide personalized pain management in Lancaster, PA, to help you break free from that daily struggle. With proven, non-surgical treatments and care that truly listens, you can move forward with comfort, confidence, and control.

Dr. Lisa Makrides

Meet Dr. Lisa Makrides: Your Local Pain Specialist


When pain takes over your life, you need more than a quick appointment and a prescription. You need someone who listens, understands, and creates a plan that’s truly yours. With Dr. Makrides as your partner, you’ll have a guide who knows how to help you take back control and get back to the life you’ve been missing.


Dr. Lisa Makrides, MD, PC, graduated Magna Cum Laude from the University of Delaware before earning her medical degree from Thomas Jefferson Medical College in Philadelphia. She completed her anesthesia training at Mount Sinai Hospital and has been board-certified in both laser specialty care and anesthesiology since 2008.

“She has changed my life, and I couldn’t be happier with her. I went from barely being able to walk to enjoying outdoor activities again.”

– Michael H., Lancaster.

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CONDITIONS WE TREAT

At Makrides Aesthetics, our pain management services in Lancaster, PA, are designed to do more than ease discomfort — they help restore mobility, improve quality of life, and give you lasting relief. Explore the conditions we treat below.  

Back Pain and Sciatica

Targeted therapies to ease spine and nerve pain.

Neck Pain

Relieve tension and restore mobility.

Joint Pain

Reduce swelling and improve movement.

Pain Syndromes and Fibromyalgia

Whole-person care for widespread pain and fatigue.

Plantar Fasciitis

Relieve heel and foot pain for easier steps.

Neuromodulation

Advanced therapies for nerve-related pain.

Sports Injury

Expert care for sports-related injuries in Lancaster.

Arthritis

Minimize stiffness and protect joint health

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PERSONALIZED PAIN RELIEF TREATMENTS

Finding relief doesn’t have to mean surgery or relying on medications alone. We offer proven, minimally invasive treatments that address pain at its source and help you move forward with confidence.

Ketamine therapy

Used for certain chronic pain conditions and treatment-resistant depression, ketamine therapy uniquely targets the nervous system. It’s administered under careful medical supervision to ensure safety and the best possible results.


How it helps:
Can provide relief for patients who haven’t responded to standard treatments.

Prolotherapy

Prolotherapy is a type of regenerative injection therapy that stimulates your body’s natural healing process to repair ligaments, tendons, and joints.


How it helps:
Non-surgical approach that strengthens and stabilizes injured or weakened tissue over time.

Nerve block therapy

​​A targeted injection therapy that interrupts pain signals from specific nerves, offering fast, localized relief.


How it helps:
Pinpoints the source of pain for immediate, focused results without affecting the rest of the body.

Regenerative medicine (PRP, biologics)

Platelet-rich plasma (PRP) and biologic treatments use components from your own body to reduce inflammation and promote healing. 


How it helps:
Regenerative medicine harnesses your body’s repair mechanisms for long-term recovery.

Lifestyle guidance & PT referrals

Your treatment plan may also include guidance on posture, movement, and activity, plus referrals to trusted physical therapy providers when needed.


How it helps:
Addresses the root causes of pain to support lasting results and overall wellness.

Customized Care for Pain-Free Living

Every plan is designed with your life in mind. Dr. Makrides looks beyond symptoms to choose the approach that supports your goals — whether that’s keeping up with family, returning to work, or simply waking up without pain. 

Discover the Right Treatment for You

Why Lancaster Patients Choose Dr. Makrides

The difference begins during your first appointment. You’re not rushed, talked over, or handed a one-size-fits-all plan. You’re heard — every symptom, every concern, every goal.

“The only doctor who correctly diagnosed my piriformis syndrome. For years, I was told I suffered from sciatica. She is amazing. I am now able to walk without pain. She is the real deal!”



Dedtra D.

“Dr. Makrides has been helpful, professional, and the backbone of my care. She takes her time with me, very accessible if needed, and will go out of her way to make sure that I get any referrals done at the time of service. I highly recommend seeking her care. She’s the easiest to communicate with, in any case.”

Terra R.

With Dr. Makrides, you’re not just another patient. You’re a partner in your own recovery — and you’ll always have a physician who combines medical expertise with genuine compassion.

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Feel Good in Your Skin — Aesthetic Services

Looking your best isn’t vanity — it’s confidence. Our aesthetic treatments enhance your natural features, refresh your appearance, and help you feel your most radiant in every setting.



  • Facial rejuvenation – Smooths, tightens, and revitalizes skin for a fresh, youthful look without surgery.

  • PRP for skin & hair – Uses your body’s platelet-rich plasma to improve skin texture and stimulate healthy hair growth naturally.

  • Laser rejuvenation – Targets fine lines, uneven tone, and surface imperfections to reveal clearer, more radiant skin.


  • Laser hair removal – Offers lasting reduction of unwanted hair for smooth, carefree skin year-round.
Explore Our Aesthetic Services »

Frequently Asked Questions — Pain Management in Lancaster, PA

  • When should I see a pain management doctor?

    If pain hasn’t improved after a few weeks, limits your ability to move or work, or affects your quality of life, it’s time to see a pain management specialist. The sooner we address it, the faster you can get back to living without limits.


  • What treatment options are available for my specific type of pain?

    We offer a full range of non-surgical options — from targeted injections and nerve blocks to regenerative therapies like PRP and ketamine — all tailored to your unique condition, goals, and lifestyle.


  • How should I prepare for my pain management appointment?

    Bring a list of your symptoms, any previous treatments or medications, and your goals for recovery. The more we know, the faster we can create a treatment plan that works for you.


Still Have Questions?

Serving Lancaster County and Beyond

We’re proud to serve patients in Lancaster, Ephrata, Lititz, Elizabethtown, York, Reading, Harrisburg — as well as many communities throughout Central Pennsylvania.

Serving Lancaster County and Beyond

We’re proud to serve patients in Lancaster, Ephrata, Lititz, Elizabethtown, York, Reading, Harrisburg — as well as many communities throughout Central Pennsylvania.

Do More Than Manage Your Pain

With Dr. Lisa Makrides, MD, PC, an expert in pain management in Lancaster, PA, life feels lighter again. You move through your days with confidence instead of hesitation, joy instead of frustration. The moments you once missed are yours again — fully present, fully engaged, and finally free. 



Start your journey today and see what life feels like without the weight of pain.

Get Started Today!

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